Nociceptin/orphanin-FQ (NOCI) together with its receptor NOP are widely expressed in cortical and subcortical motor areas and it is known that NOCI acts as an anxiolytic attenuating the behavioral inhibition of animals acutely exposed to str...

A theoretical paper proposes applications of golden proportion principles to physiological diagnostics. It outlines proposed metrics and discusses validation needs and limitations.

Maintaining Cardiac Hemodinamy and Electrophysiology

Swimming is a human activity that relies heavily on individual physiological capabilities. In fact, the swimming general performance equation, proposed several years ago by di Prampero 1, highlighted the en...

Neosaxitoxin (NeoSTX) is a specific high-affinity inhibitor of voltage-dependent sodium channels, which has shown excellent results as a local anesthetic in various pathologies and post-operative protocols, since it effect is long-lasting an...

The brain is one of the most complicated body segments which processes almost all activities in human body. Excessive physical and mental overloads can cause brain fatigue and may put the brain health at risk of various diso...

The brain is the most complex organ which governs almost all activities in human body. Thus, the mental fitness has high level of importance in every day workouts. The good activities for long-term brain health include performing regular exe...

A commentary addresses the benefits and risks of vigorous exercise over time from a physiological perspective, discussing adaptation, monitoring, and individualized recommendations.

The pineal gland constitutes a major neuroendocrine organ in the brain. By mean of its neurohormone melatonin it transduces exogenous signals such as circadian and seasonal variations of light and temperature into proper hormonal changes whi...

This opinion challenges fatalistic framing of hepatic cancer prognosis. It advocates for nuanced discussion of staging, treatment advances, and supportive care, with clear communication to patients and families.

Obesity generally accounts for a pathophysiology condition at which excessive body fats get accumulated in body parts. Among different - causes, ambient temperature such as cold environment can dramatically develop obesity in different i...

Walking is the best possible exercise to promote fitness. However, ambient temperature has an impact on walking regimen and performing exercise in different biological conditions can be challenging tasks. For example, both cold and hot tempe...

Study Design: Prospective study, simple crossover design. Background: Proprioception is a cornerstone for maintaining joint and postural stability. Dynamic stability is particularly ...

Body mass index (BMI) seemingly is an important scale for the body types determination in individual with different ethnicity. Accordingly, individual with BMI< 18.5 are classified as slim or underweight and people with BMI between 18.5...

An opinion editorial comments on indexing and visibility in scholarly communication. It encourages quality, openness, and ethical practices as pathways to discoverability and impact, with concrete steps for journals and authors.

Physiological changes in musculature allow widespread movements in human body. Correspondingly, varying in muscle prototypes characterise direct different training paradigms in therapeutics practice or can governs athletic...

Overusing the computer and internet can yield several health problems. The enhanced use of computer on can impact on both physiological and psychiatric health factors. It is accompanies with bad posture, musculoskeletal pains, obesity, weake...

Objective: Soccer has a reduced overall recovery time. If these situations are not properly controlled they can cause the athlete chronic fatigue, an increase in delayed-onset muscle soreness (DOMS) and thus result in a ...

A short editorial underscores the bridge between basic sciences and clinical medicine. It emphasizes how mechanistic knowledge informs diagnostics and therapy, and calls for curricula that strengthen this continuum.

Objective: The purpose of this study is to evaluate the use of paralytic shellfish poisoning toxin in a patient with arthrofibrosis of the knee. Arthrofibrosis is a common complication of knee surgery that tends to mani...

Isatin (1H-indole-2,3-dione ) and derivatives demonstrate a diverse array of biological activities. Isatin and 5-halo derivatives has reacted to form the schiff’s bases , mannich bases and friedal craft alkylation’s to form C-C, C-N, C=N bon...

The present study was aimed to evaluate the effect of Consciousness Energy Healing Treatment on plant callus of Mandukparni (Centellaasiatica), Katsarika (Barleriacristata), and Amla (Phyllanthus emblica) in Murashige & Skoog liquid medi...

Objective: Use "The 11 +" warm-up program in female players of the National Chilean Sub-17 Football team in order to analyze morpho – physiological variables. The implementation of this training program will generate ...

Following ocular trauma and retinal detachment, gliotic changes in the retina may develop over the subsequent month, a process known as PVR (proliferative vitreoretinopathy). There have been no successful therapeutic interventions to inhibit...

A reflective piece touches on core physiological concepts and experimental approaches, linking basic mechanisms to clinical insight and education.

Objective To evaluate the effect of a single intraarticular dose of Gonyautoxins for pain control after Total Knee Arthroplasty (TKA). Subjects 30 consecutive patients with osteoarth...

Background: The core interthreshold zone (CIZ) is defined as the range between core temperature (Tc) at the onset of shivering and the Tc at the onset of sweating under consistent mean skin temperatures of 28°C to 30°C....